Ketoconazole (Nizoral) for Angular Cheilitis
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Definition: Ketoconazole is a synthetic antifungal drug used to prevent and treat fungal skin infections, especially in immunocompromised patients such as those with AIDS or those on chemotherapy. Ketoconazole is sold commercially as an anti-dandruff shampoo, topical cream, and oral tablet, under the trademark name Nizoral by Ortho-McNeil Pharmaceutical in the United States, Australia and Canada, as Sebizole by Douglas Pharmaceuticals in Australia and New Zealand and as Ketomed in Latin America. Angular cheilitis (also called perlèche, cheilosis or angular stomatitis) is an inflammatory lesion at the labial commissure, or corner of the mouth, and often occurs bilaterally. The condition manifests as deep cracks or splits. In severe cases, the splits can bleed when the mouth is opened and shallow ulcers or a crust may form. (SOURCE: Wikipedia)
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